Mean Differences of TNF-α and PIBF Levels in < 12th Gestational Weeks Pregnant Women with Imminent Abortion

Yohana Suganda, Aisyah Elyanti, Roza Sriyanti

Background: The aim of the study mean difference of TNF-α and PIBF levels in less than 12th gestational weeks pregnant women with imminent abortion. Methods: The study was conducted using a cross sectional study. The study was conducted at Bhayangkara Hospital, dr Reksodiwiryo Hospital, Ibnu Sina Hospital and dr Rasidin Hospital, Padang City, West Sumatera Province, Indonesia from December 2017-December 2018. The population in this study were all patient with imminent abortion and normal pregnancy with sample size 36 people. Sampling technique with consecutive sampling. TNF- α and PIBF measurement used ELISA test. Hypothesis test used independent sample T test. A two-tailed P-value of <0.05 was considered statistically significant. Results: The results of the study known mean TNF-α level in imminent abortion (3.75 ± 1.03 ng / ml) and at <12th gestational weeks (3.03 ± 0.88 ng / ml). The mean PIBF in imminent abortion (33.92 ± 9.88 ng / ml) and at at <12th gestational weeks (43.41 ± 13.52 ng / ml). There were mean difference of TNF-α and PIBF levels in less than 12th gestational weeks pregnant women with imminent abortion (p<0.05). Conclusion: This analysis confirmed there were mean difference of TNF-α and PIBF levels in less than 12th gestational weeks pregnant women with imminent abortion.